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Sibutramine (trade name Meridia in the USA, Leptos in India, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity, as an appetite suppressant. It is a centrally-acting serotonin-norepinephrine reuptake inhibitor structurally related to amphetamines, although its mechanism of action is distinct.
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3 edits since May 19, 2008. Last edited Jul 27, 2008 by SHAHINOVE (1).
Clorazepate (marketed under the brand names Tranxene and Tranxilium), is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Clorazepate was discontinued in February 2006 in the United Kingdom.
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15 edits since May 19, 2008. Last edited Jul 27, 2008 by Lyrl (2).
Sulindac is a non-steroidal anti-inflammatory drug of the arylalkanoic acid class that is marketed in the UK & U.S. by Merck as Clinoril. Like other NSAIDs, it is useful in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in the body to the active NSAID. More specifically, the agent is converted by liver enzymes to a sulfide that is excreted in the bile and then reabsorbed from the intestine. This is thought to help maintain constant blood levels with reduced gastrointestinal side effects. Some studies have shown sulindac to be relatively less irritating to the stomach than other NSAID's except for drugs of the COX-2 inhibitor class . The exact mechanism of its NSAID properties is unknown, but it is thought to act on enzymes COX-1 and COX-2, inhibiting prostaglandin synthesis.
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2 edits since May 19, 2008. Last edited Jul 27, 2008 by anonymous (1073).
The chemical compound ammonium nitrate, the nitrate of ammonia with the chemical formula NH4NO3, is a white powder at room temperature and standard pressure. It is commonly used in agriculture as a high-nitrogen fertilizer, and it has also been used as an oxidizing agent in explosives, including improvised explosive devices.
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18 edits since May 19, 2008. Last edited Jul 27, 2008 by AndersBot (4).
Omalizumab (marketed under the name Xolair) is a monoclonal antibody made by Genentech / Novartis and used mainly in allergy-related asthma therapy, with the purpose of reducing allergic hypersensitivity. Xolair (Omalizumab) is a recombinant DNA-derived humanized IgG1k monoclonal antibody that selectively binds to human immunoglobulin E (IgE). IgE is commonly involved with allergies when present in high amounts in the body.
3 edits since May 19, 2008. Last edited Jul 27, 2008 by anonymous (1073).
Eu(fod) is the chemical compound with the formula Eu(OCC(CH3)3CHCOCF2CF2CF3)3, also called Eu(fod)3. This coordination compound is used primarily as a shift reagent in NMR spectroscopy. It is the premier member of the lanthanide shift reagents and was popular in the 1970s and 1980s> The availability of higher magnetic field spectrometers have made this application obsolete because they can better resolve signals.
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3 edits since May 19, 2008. Last edited Jul 27, 2008 by THEN WHO WAS PHONE? (2).
Ethyl formate is an ester formed when ethanol reacts with formic acid. It is also known as ethyl methanoate because ethanol (an alcohol) and methanoic acid (a carboxylic acid also known as formic acid) are used to form it. Ethyl formate has the characteristic smell of rum. This molecule is also responsible for the flavor of raspberries.
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2 edits since May 19, 2008. Last edited Jul 27, 2008 by Zzuuzz (1).
Suxamethonium chloride (also known as succinylcholine, scoline, or colloquially as sux) is a medication widely used in emergency medicine and anesthesia to induce muscle relaxation, usually to make endotracheal intubation possible. Suxamethonium is sold under several trade names such as Anectine, and may be referred to as "sux" for short.
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5 edits since May 19, 2008. Last edited Jul 27, 2008 by KTyson (1).
Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.
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2 edits since May 19, 2008. Last edited Jul 27, 2008 by Arcadian (275).
Buprenorphine is an opioid drug with partial agonist and antagonist actions. Buprenorphine hydrochloride was first marketed in the 1980s by Reckitt & Colman (now Reckitt Benckiser) as an analgesic, available generally as Temgesic 0.2 mg sublingual tablets, and as Buprenex in a 0.3 mg/ml injectable formulation. In October 2002, the Food and Drug Administration (FDA) of the United States of America additionally approved Suboxone and Subutex, buprenorphine's high-dose sublingual pill preparations for opioid addiction, and as such the drug is now also used for this purpose. In the USA, it has been a Schedule III drug under the United Nations' Convention on Psychotropic Substances since it was rescheduled from Schedule V (the schedule with the lowest restrictions and penalties in the USA) just before FDA approval of Suboxone and Subutex. In the recent years, buprenorphine has been introduced in most European countries as a transdermal formulation ("patch") for the treatment of chronic pain.
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13 edits since May 19, 2008. Last edited Jul 27, 2008 by anonymous (1073).
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