Modafinil (Provigil) is a stimulant-like drug manufactured by Cephalon, and is approved by the FDA for the treatment of narcolepsy. Modafinil, like other stimulants, increases the release of monoamines but also elevates hypothalamic histamine levels, leading some researchers to consider Modafinil a "wakefulness promoting agent" rather than a classic amphetamine-like stimulant (as evidenced by the difference in c-fos distribution caused by modafinil as compared to amphetamine). Modafinil is also indicated, though not approved, in the treatment of Attention-Deficit Hyperactivity Disorder (ADHD), shift-work sleep disorder, depression, cocaine addiction, Parkinson's Disease, schizophrenia, and disease-related fatigue. By law, however, Cephalon is not allowed to market Modafinil for conditions other than those officially approved by the FDA.
22 edits since May 19, 2008. Last edited Jul 11, 2008 by anonymous (1073).
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