Thioridazine is a piperidine antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis. It is available from various companies under the names Mellaril, Novorizadine, and Thioril. Due to concerns about cardiotoxicity and retinopathy at high doses this drug is not commonly prescribed, reserved for patients who have failed to respond to, or have contraindications for, more widely used antipyschotics. A serious side effect is the potentially fatal neuroleptic malignant syndrome. It exerts its actions through a central adrenergic-blocking, a dopamine-blocking and minor anticholinergic activity.
4 edits since May 19, 2008. Last edited Jul 22, 2008 by SmackBot (107).
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